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A novel approach to phylogenetic tree construction using stochastic optimization and clustering
- Source :
- BMC Bioinformatics, Vol 7, Iss Suppl 4, p S24 (2006), BMC Bioinformatics
- Publication Year :
- 2006
- Publisher :
- BMC, 2006.
-
Abstract
- Background The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational biology. Results A new phylogenetic tree construction method from a given set of objects (proteins, species, etc.) is presented. As an extension of ant colony optimization, this method proposes an adaptive phylogenetic clustering algorithm based on a digraph to find a tree structure that defines the ancestral relationships among the given objects. Conclusion Our phylogenetic tree construction method is tested to compare its results with that of the genetic algorithm (GA). Experimental results show that our algorithm converges much faster and also achieves higher quality than GA.
- Subjects :
- Theoretical computer science
Biology
Machine learning
computer.software_genre
lcsh:Computer applications to medicine. Medical informatics
Biochemistry
Pattern Recognition, Automated
Biomimetics
Structural Biology
Computational phylogenetics
Genetic algorithm
Animals
Cluster Analysis
Social Behavior
Cluster analysis
Molecular Biology
lcsh:QH301-705.5
Phylogeny
Stochastic Processes
Models, Statistical
Behavior, Animal
Models, Genetic
Phylogenetic tree
Ants
business.industry
Research
Applied Mathematics
Ant colony optimization algorithms
Biological Evolution
Computer Science Applications
ComputingMethodologies_PATTERNRECOGNITION
Tree structure
lcsh:Biology (General)
Tree rearrangement
lcsh:R858-859.7
Stochastic optimization
Artificial intelligence
business
computer
Algorithms
Subjects
Details
- Language :
- English
- ISSN :
- 14712105
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- BMC Bioinformatics
- Accession number :
- edsair.doi.dedup.....f34808d9b390e646bd8ebf987f840feb