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A novel approach to phylogenetic tree construction using stochastic optimization and clustering

Authors :
Yixin Chen
Ling Qin
Ling Chen
Yi Pan
Source :
BMC Bioinformatics, Vol 7, Iss Suppl 4, p S24 (2006), BMC Bioinformatics
Publication Year :
2006
Publisher :
BMC, 2006.

Abstract

Background The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational biology. Results A new phylogenetic tree construction method from a given set of objects (proteins, species, etc.) is presented. As an extension of ant colony optimization, this method proposes an adaptive phylogenetic clustering algorithm based on a digraph to find a tree structure that defines the ancestral relationships among the given objects. Conclusion Our phylogenetic tree construction method is tested to compare its results with that of the genetic algorithm (GA). Experimental results show that our algorithm converges much faster and also achieves higher quality than GA.

Details

Language :
English
ISSN :
14712105
Volume :
7
Database :
OpenAIRE
Journal :
BMC Bioinformatics
Accession number :
edsair.doi.dedup.....f34808d9b390e646bd8ebf987f840feb