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Transcriptional regulation of strigolactone signalling in Arabidopsis
- Source :
- Nature. 583:277-281
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- Plant hormones known as strigolactones control plant development and interactions between host plants and symbiotic fungi or parasitic weeds1–4. In Arabidopsis thaliana and rice, the proteins DWARF14 (D14), MORE AXILLARY GROWTH 2 (MAX2), SUPPRESSOR OF MAX2-LIKE 6, 7 and 8 (SMXL6, SMXL7 and SMXL8) and their orthologues form a complex upon strigolactone perception and play a central part in strigolactone signalling5–10. However, whether and how strigolactones activate downstream transcription remains largely unknown. Here we use a synthetic strigolactone to identify 401 strigolactone-responsive genes in Arabidopsis, and show that these plant hormones regulate shoot branching, leaf shape and anthocyanin accumulation mainly through transcriptional activation of the BRANCHED 1, TCP DOMAIN PROTEIN 1 and PRODUCTION OF ANTHOCYANIN PIGMENT 1 genes. We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling. These findings reveal an unanticipated mechanism through which a transcriptional repressor of hormone signalling can directly recognize DNA and regulate transcription in higher plants. Many of the molecular targets of strigolactones—plant hormones involved in development and in interactions with symbiotic and parasitic organisms—are uncovered, revealing how strigolactones function and an intriguing role for self-regulation of a downstream transcription factor.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Transcription, Genetic
Arabidopsis
Strigolactone
Genes, Plant
01 natural sciences
Anthocyanins
Lactones
03 medical and health sciences
Plant Growth Regulators
Gene Expression Regulation, Plant
Transcription (biology)
Transcriptional regulation
Promoter Regions, Genetic
Gene
Transcription factor
Regulation of gene expression
Multidisciplinary
biology
Arabidopsis Proteins
fungi
food and beverages
Promoter
biology.organism_classification
Cell biology
Plant Leaves
030104 developmental biology
Heterocyclic Compounds, 3-Ring
Plant Shoots
Signal Transduction
Transcription Factors
010606 plant biology & botany
Subjects
Details
- ISSN :
- 14764687 and 00280836
- Volume :
- 583
- Database :
- OpenAIRE
- Journal :
- Nature
- Accession number :
- edsair.doi.dedup.....f326da8011a5905e475b53214df24b97