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Retrospective Multicenter Matched Controlled Comparison of Endoscopic Retrograde Cholangiopancreatography in Pediatric Patients: A 10-year Experience
- Source :
- Journal of Pediatric Gastroenterology & Nutrition. 70:568-573
- Publication Year :
- 2020
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2020.
-
Abstract
- INTRODUCTION This study was designed to evaluate outcomes in pediatric patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) as compared with an American Society of Gastrointestinal Endoscopy (ASGE) complexity grade-matched adult cohort. METHOD In this retrospective case-control study, ERCPs performed in pediatric patients from January 2008 to December 2018 in 2 tertiary referral hospitals were compared with a complexity-matched adult control group with similar procedural indications. Primary outcomes included the clinical success rate, technical success rate, and complication rate. Secondary outcomes included postprocedural admission rates, mode of sedation, procedure time, fluoroscopy time, hospitalization length, and the number of repeat procedures. RESULTS Two hundred thirty-two ERCPs performed in 110 pediatric patients (average age 13.3) and 318 ERCPs performed in 160 ASGE grade-matched adult controls (average age 47.2 years) were analyzed. All procedures were therapeutic. There was no difference in the technical success rate (P = 0.2), clinical success rate (P = 0.5), complication rates (P = 0.1), and fluoroscopy time (P = 0.4), between the pediatric and adult cohorts. General anesthesia use and length of stay were significantly higher in the pediatric group (P = 0.0001). In subgroup analysis, technical (P = 0.2) and clinical success (P = 0.2) as well as complication rates (P = 0.6) were comparable between patients 10 years or less and patients 11 to 18 years within pediatric cohort. CONCLUSIONS ERCP in pediatric cohorts appears to be safe and effective with equivalent outcomes relative to an ASGE complexity-matched adult cohort. Pediatric patients are more likely to require general anesthesia and have a longer average length of stay relative to adult controls.
- Subjects :
- Adult
Pediatrics
medicine.medical_specialty
Adolescent
Referral
Sedation
Subgroup analysis
Endoscopy, Gastrointestinal
Cohort Studies
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
medicine
Humans
Fluoroscopy
Child
Retrospective Studies
Gastrointestinal endoscopy
Cholangiopancreatography, Endoscopic Retrograde
Endoscopic retrograde cholangiopancreatography
medicine.diagnostic_test
business.industry
Gastroenterology
Middle Aged
Case-Control Studies
Pediatrics, Perinatology and Child Health
Cohort
030211 gastroenterology & hepatology
medicine.symptom
business
Complication
Subjects
Details
- ISSN :
- 15364801 and 02772116
- Volume :
- 70
- Database :
- OpenAIRE
- Journal :
- Journal of Pediatric Gastroenterology & Nutrition
- Accession number :
- edsair.doi.dedup.....f2d750953eb9c140ec332a9fa22d0052