Back to Search
Start Over
Impact of Anastomotic Leakage on Overall and Disease-free Survival After Surgery for Gastric Carcinoma: A Systematic Review
- Source :
- Anticancer Research. 40:619-624
- Publication Year :
- 2020
- Publisher :
- Anticancer Research USA Inc., 2020.
-
Abstract
- Background/aim Gastric cancer is the fifth most frequently diagnosed cancer and the second most common cause of cancer-related death. The only potentially curative treatment is surgical resection, which is associated with potentially severe complications, such as anastomotic leakage. The aim of this systematic review was to evaluate the relationship between anastomotic leakage and overall and disease-free survival after surgery for gastric cancer. Materials and methods A systematic literature search was performed and 7 articles published between 2010 and 2019 were included, including a total of 7,167 patients. Results Among the included studies the frequency of anastomotic leakage ranged from 6 to 41%. Patients affected by anastomotic leakage had an overall survival ranging between 4.1 and 97.6 months, whereas patients who did not experience anastomotic leakage had an overall survival between 23 and 109.5 months. Conclusion Closer follow-up or even more aggressive oncological therapy may be considered for patients affected by anastomotic leakage after surgery for gastric cancer.
- Subjects :
- Male
Surgical resection
Cancer Research
Disease free survival
medicine.medical_specialty
Anastomotic Leak
Gastric carcinoma
gastric cancer
anastomotic leakage
disease-free survival
overall survival
review
Disease-Free Survival
03 medical and health sciences
0302 clinical medicine
Stomach Neoplasms
Overall survival
medicine
Humans
Aged
business.industry
Cancer
General Medicine
Middle Aged
medicine.disease
Surgery
Oncology
Anastomotic leakage
Curative treatment
030220 oncology & carcinogenesis
Female
business
Systematic search
Subjects
Details
- ISSN :
- 17917530 and 02507005
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Anticancer Research
- Accession number :
- edsair.doi.dedup.....f2c35f478e78b653022720bf0d87ddb2