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Lower omega-3 status associated with higher erythrocyte distribution width and neutrophil-lymphocyte ratio in UK Biobank cohort
- Source :
- Prostaglandins, Leukotrienes and Essential Fatty Acids. 192:102567
- Publication Year :
- 2023
- Publisher :
- Elsevier BV, 2023.
-
Abstract
- High red blood distribution width (RDW) is associated with decreased red blood cell deformability, and high neutrophil-lymphocyte ratio (NLR) is a biomarker of systemic inflammation and innate-adaptive immune system imbalance. Both RDW and NLR are predictors of chronic disease risk and mortality. Omega-3 index (O3I) values have previously been shown to be inversely associated with RDW and NLR levels. Our objective was to determine if total plasma long chain omega-3 fatty acids (Omega3%) measured in the UK Biobank cohort were associated with RDW and NLR values. RDW- and NLR-relationships with Omega3% were characterized in 109,191 adults (58.4% female). RDW- and NLR-Omega3% relationships were inversely associated with Omega3% (both p
- Subjects :
- Clinical Biochemistry
Cell Biology
Subjects
Details
- ISSN :
- 09523278
- Volume :
- 192
- Database :
- OpenAIRE
- Journal :
- Prostaglandins, Leukotrienes and Essential Fatty Acids
- Accession number :
- edsair.doi.dedup.....f297863e595b68ad06f94b9c872eda63