MICA∗078: A novel allele identified in a Moroccan individual affected by celiac disease

Authors :: Alessia Colanardi
A. Essaid
Imane Benelbarhdadi
Tiziana Del Beato
Daniela Piancatelli
Alessandra Tessitore
Rajae El Aouad
Pierluigi Sebastiani
Khadija Oumhani
Source :: Human immunology 76 (2015): 438–441. doi:10.1016/j.humimm.2015.03.013, info:cnr-pdr/source/autori:Piancatelli D.; Oumhani K.; Benelbarhdadi I.; Del Beato T.; Colanardi A.; Sebastiani P.; Tessitore A.; El Aouad R.; Essaid A./titolo:MICA*078: A novel allele identified in a Moroccan individual affected by celiac disease/doi:10.1016%2Fj.humimm.2015.03.013/rivista:Human immunology/anno:2015/pagina_da:438/pagina_a:441/intervallo_pagine:438–441/volume:76
Publication Year :: 2015
Publisher :: Elsevier BV, 2015.
Abstract: A novel MICA allele, MICA*078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA*078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G -> A), resulting in one amino acid change at codon 142 (V -> I) of MICA gene (compared to MICA*002:01), located in the alpha 2-domain, in which V142 is the common residue. (C) 2015 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

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