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Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp
- Source :
- Marine Drugs, Marine Drugs, Vol 11, Iss 11, Pp 4585-4593 (2013), Marine Drugs; Volume 11; Issue 11; Pages: 4585-4593
- Publication Year :
- 2013
- Publisher :
- MDPI AG, 2013.
-
Abstract
- A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells.
- Subjects :
- food.ingredient
Cladiella
Stereochemistry
Coral
litophynin
eunicellin
cladieunicellin
cytotoxicity
Pharmaceutical Science
Article
food
Cell Line, Tumor
Anthozoa
Drug Discovery
Botany
Animals
Humans
Colorectal adenocarcinoma
Spectral data
lcsh:QH301-705.5
Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Eunicellin
biology
biology.organism_classification
lcsh:Biology (General)
Diterpenes
Drug Screening Assays, Antitumor
Subjects
Details
- ISSN :
- 16603397
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Marine Drugs
- Accession number :
- edsair.doi.dedup.....f20e8c090c9318b09d3add3f48382993