Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip

Authors :: Tran Quang Hung
Anders Wolff
Yi Sun
Carl Esben Poulsen
Wai Hoe Chin
Than Linh-Quyen
Dang Duong Bang
Source :: Hung, T Q, Sun, Y, Poulsen, C E, Than Linh, Q, Chin, W H, Bang, D D & Wolff, A 2015, ' Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip ', Lab on a Chip, vol. 15, no. 11, pp. 2445-2451 . https://doi.org/10.1039/c5lc00176e
Publication Year :: 2015
Publisher :: Royal Society of Chemistry (RSC), 2015.
Abstract: A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.

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