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The independent factors associated with oxygen therapy in COVID-19 patients under 65 years old
- Source :
- PLoS ONE, Vol 16, Iss 1, p e0245690 (2021), PLoS ONE
- Publication Year :
- 2021
- Publisher :
- Public Library of Science (PLoS), 2021.
-
Abstract
- Background The number of hospitalized young coronavirus disease 2019 (COVID-19) patients has increased significantly. However, specific data about COVID-19 patients under 65 years old who are admitted to the hospital are scarce. Methods The COVID-19 patients under 65 years old who were admitted to the hospital in Sichuan Province, Renmin Hospital of Wuhan University, and Wuhan Red Cross Hospital were included in this study. Demographic information, laboratory data and clinical treatment courses were extracted from electronic medical records. Risk factors associated with oxygen therapy were explored. Results Eight hundred thirty-three COVID-19 patients under 65 years old were included. Of the included patients, 29.4% had one or more comorbidities. Oxygen therapy was required in 63.1% of these patients, and the mortality was 2.9% among the oxygen therapy patients. Fever (odds ratio [OR] 2.072, 95% confidence interval [CI] 1.312–3.271, p = 0.002), dyspnea (OR 2.522, 95% CI 1.213–5.243, p = 0.013), chest distress (OR 2.278, 95% CI 1.160–4.473, p = 0.017), elevated respiratory rate (OR 1.114, 95% CI 1.010–1.228, p = 0.031), and decreased albumin (OR 0.932, 95% CI 0.880–0.987, p = 0.016) and globulin levels (OR 0.929, 95% 0.881–0.980, p = 0.007) were independent factors related to oxygen therapy. Conclusions Oxygen therapy is highly required in COVID-19 patients under 65 years old who are admitted to the hospital, but the success rate is high. Respiratory failure-related symptoms, elevated respiratory rate, low albumin and globulin levels, and fever at admission are independent risk factors related to the requirement of oxygen.
- Subjects :
- Male
Viral Diseases
Physiology
Epidemiology
medicine.medical_treatment
Fevers
030204 cardiovascular system & hematology
Biochemistry
White Blood Cells
0302 clinical medicine
Medical Conditions
Animal Cells
Risk Factors
Oxygen therapy
Medicine and Health Sciences
Medicine
030212 general & internal medicine
Lymphocytes
Respiratory system
Multidisciplinary
Medical record
Respiration
Age Factors
Middle Aged
Hospitalization
Distress
Chemistry
Infectious Diseases
Treatment Outcome
Physical Sciences
Female
Cellular Types
Research Article
Chemical Elements
Adult
medicine.medical_specialty
China
Respiratory rate
Immune Cells
Science
Immunology
03 medical and health sciences
Signs and Symptoms
Internal medicine
Albumins
Humans
Blood Cells
business.industry
Oxygen Inhalation Therapy
Biology and Life Sciences
Proteins
COVID-19
Covid 19
Globulins
Odds ratio
Cell Biology
Confidence interval
Oxygen
Dyspnea
Medical Risk Factors
Clinical Medicine
business
Physiological Processes
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 16
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....f1f8b68bf716f2364680f0eb9fee5b48