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Antral follicle responsiveness assessed by follicular output RaTe(FORT) correlates with follicles diameter

Authors :
Camila Karsburg Bessow
Tatiane Oliveira de Souza
Rafaela Donato
Vanessa Krebs Genro
João Sabino Cunha-Filho
Rita Chapon
Source :
Journal of Ovarian Research, Vol 12, Iss 1, Pp 1-6 (2019), Journal of Ovarian Research
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

Background The antral follicle count is a marker of ovarian reserve. Follicular Output RaTe (FORT) evaluates the proportion of follicles responsive to exogenous follicle stimulating hormone (FSH) during controlled ovarian stimulation. Our objective was to evaluate whether the diameter (AFC6: ≤ 6 mm or AFC > 6: > 6 mm) of the follicular cohort could be a predictor for ovarian responsiveness, assessed by FORT, in a prospective cohort with 92 women with IVF indication, regular cycles and no abnormality in both ovaries. Results The mean age (±SD) of the women was 36.03 years (± 3.87 years), the median FORT was 43.30%. We found correlation between the FORT and AFC6 (r = − 0.237, P 0.023) but not between the FORT and AFC > 6 (r = − 0.055, P 0.602). Conclusions The inverse correlation between FORT and AFC6 suggests that those follicles were less responsive to the exogenous FSH.

Details

ISSN :
17572215
Volume :
12
Database :
OpenAIRE
Journal :
Journal of Ovarian Research
Accession number :
edsair.doi.dedup.....f1cb68a23c1dc7cb072993a7a4cab3d8
Full Text :
https://doi.org/10.1186/s13048-019-0522-4