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Mimicking biopolymers on a molecular scale: nano(bio)technology based on engineered proteins

Authors :
Stefan M. Kast
Ingo Grunwald
Hendrik Bargel
Thomas Scheibel
Klaus Rischka
Publica
Source :
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 367:1727-1747
Publication Year :
2009
Publisher :
The Royal Society, 2009.

Abstract

Proteins are ubiquitous biopolymers that adopt distinct three-dimensional structures and fulfil a multitude of elementary functions in organisms. Recent systematic studies in molecular biology and biotechnology have improved the understanding of basic functional and architectural principles of proteins, making them attractive candidates as concept generators for technological development in material science, particularly in biomedicine and nano(bio)technology. This paper highlights the potential of molecular biomimetics in mimicking high-performance proteins and provides concepts for applications in four case studies, i.e. spider silk, antifreeze proteins, blue mussel adhesive proteins and viral ion channels.

Details

ISSN :
14712962 and 1364503X
Volume :
367
Database :
OpenAIRE
Journal :
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Accession number :
edsair.doi.dedup.....f193957543c22987dc566041d8bce0dd