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Tolterodine reduces veratridine-augmented late INa, reverse-INCX and early afterdepolarizations in isolated rabbit ventricular myocytes
- Publication Year :
- 2016
- Publisher :
- Nature Publishing Group, 2016.
-
Abstract
- The augmentation of late sodium current (IRabbit ventricular myocytes were prepared. The ITol (3-120 nmol/L) concentration-dependently inhibited the normal and Ver-augmented ITol inhibits normal and Ver-augmented I
- Subjects :
- 0301 basic medicine
Male
Patch-Clamp Techniques
Tolterodine Tartrate
Heart Ventricles
Action Potentials
Muscarinic Antagonists
030204 cardiovascular system & hematology
Pharmacology
In Vitro Techniques
Sodium Channels
Sodium-Calcium Exchanger
Afterdepolarization
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
medicine
Myocyte
Animals
Pharmacology (medical)
Myocytes, Cardiac
Patch clamp
Veratridine
Sodium-calcium exchanger
Chemistry
Sodium channel
General Medicine
030104 developmental biology
Original Article
Female
Tolterodine
Rabbits
Anti-Arrhythmia Agents
medicine.drug
Sodium Channel Blockers
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....f1868f5f11a9aef4dcfa6bdb8ab81ca9