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Alcohol consumption, cigarette smoking, and endometrial cancer risk: results from the Netherlands Cohort Study
- Source :
- Cancer Causes & Control, 18(5), 551-560. Springer, Cham, Cancer Causes and Control, 5, 18, 551-560, Kongress Medizin und Gesellschaft 2007; 20070917-20070921; Augsburg; DOC07gmds241 /20070906/, Cancer Causes & Control
- Publication Year :
- 2007
- Publisher :
- Springer, Cham, 2007.
-
Abstract
- Objective: To examine the association between alcohol consumption, cigarette smoking, and endometrial cancer. Methods: In 1986, the Netherlands Cohort Study was initiated. A self-administered questionnaire on dietary habits and other cancer risk factors was completed by 62,573 women. Follow-up for cancer was established by record linkage to the Netherlands Cancer Registry. Results: After 11.3-years of follow-up, 280 incident endometrial cancer cases were available for analyses. In multivariate analysis, the rate ratio (RR) for alcohol users versus non-users was 1.06 (95% Confidence Interval (95% CI)= 0.78-1.43). There were neither dose-dependent trends nor associations with different types of beverages. The RR for former and current smokers versus never-smokers was 0.83 (95% CI = 0.58-1.20) and 0.59 (95% CI = 0.40-0.88), respectively. These estimates did not change significantly when body mass index (BMI) and age at menopause were added to the models. Conclusions: There is no association between alcohol consumption and endometrial cancer. Current smoking is associated with a reduced risk of endometrial cancer. This association is neither mediated by BMI nor by age at menopause. © 2007 Springer Science+Business Media B.V.
- Subjects :
- Cancer Research
genetic structures
Body Mass Index
Cohort Studies
Cancer risk
Cigarette smoking
Risk Factors
Epidemiology
Alcohol consumption
Netherlands
Priority journal
Risk assessment
Smoking
Cancer registry
Middle Aged
Menopause
ddc: 610
Body mass
Oncology
Health
Female
Cohort analysis
Alcohol
Cohort study
Adult
medicine.medical_specialty
Alcohol Drinking
Food and Chemical Risk Analysis
Major clinical study
Disease association
Endometrium cancer
Environmental health
medicine
Humans
Risk factor
Beverage
Endometrial neoplasms
Aged
Gynecology
Original Paper
business.industry
Questionnaire
Endometrial cancer
Confidence interval
Follow up
medicine.disease
Diet
Multivariate analysis
business
Body mass index
Controlled study
Cancer incidence
Contraceptives, Oral
Subjects
Details
- Language :
- English
- ISSN :
- 15737225 and 09575243
- Volume :
- 18
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Cancer Causes & Control
- Accession number :
- edsair.doi.dedup.....f11cf278a4eb0ee7dfc0143c07689f13