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An Approach to the Diastereoselective Synthesis of Cyclohexane-1,3-dicarboxamide Derivatives via a Pseudo Five-Component Reaction Based on Diketene
- Source :
- Synlett. 29:225-229
- Publication Year :
- 2017
- Publisher :
- Georg Thieme Verlag KG, 2017.
-
Abstract
- A one-pot pseudo five-component reaction for the synthesis of 2-aryl-4-hydroxy-4-methyl-6-oxo-N 1,N 3-dialkylcyclohexane-1,3-dicarboxamide derivatives involving different primary amines, various aromatic aldehydes, and diketene in the presence of triethylamine with high yields is achieved.
- Subjects :
- diketene
multicomponent reaction
Primary (chemistry)
one-pot reaction
Cyclohexane
010405 organic chemistry
Component (thermodynamics)
Organic Chemistry
Cyclohexanone
010402 general chemistry
01 natural sciences
0104 chemical sciences
chemistry.chemical_compound
chemistry
One pot reaction
diastereoselective synthesis
Organic chemistry
cyclohexanone
Triethylamine
Diketene
Subjects
Details
- ISSN :
- 14372096 and 09365214
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Synlett
- Accession number :
- edsair.doi.dedup.....f117e24ff412cf1adbcf88f2f1289e92
- Full Text :
- https://doi.org/10.1055/s-0036-1590980