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An Approach to the Diastereoselective Synthesis of Cyclohexane-1,3-dicarboxamide Derivatives via a Pseudo Five-Component ­Reaction Based on Diketene

Authors :
Hossein A. Oskooie
Bahareh Talaei
Majid M. Heravi
Atieh Rezvanian
Source :
Synlett. 29:225-229
Publication Year :
2017
Publisher :
Georg Thieme Verlag KG, 2017.

Abstract

A one-pot pseudo five-component reaction for the synthesis of 2-aryl-4-hydroxy-4-methyl-6-oxo-N 1,N 3-dialkylcyclohexane-1,3-dicarboxamide derivatives involving different primary amines, various aromatic aldehydes, and diketene in the presence of triethylamine with high yields is achieved.

Details

ISSN :
14372096 and 09365214
Volume :
29
Database :
OpenAIRE
Journal :
Synlett
Accession number :
edsair.doi.dedup.....f117e24ff412cf1adbcf88f2f1289e92
Full Text :
https://doi.org/10.1055/s-0036-1590980