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In vitro effects of four polysaccharides containing β-D-Glup on intestinal function
- Source :
- International Journal of Food Properties, Vol 22, Iss 1, Pp 1064-1076 (2019)
- Publication Year :
- 2019
- Publisher :
- Taylor & Francis Group, 2019.
-
Abstract
- Plant polysaccharides exert a wide range of biological effects on the intestinal function. In this study, four polysaccharides containing β-D-Glup, including Dendrobium officinale polysaccharide (DOP), Dendrobium aphyllum polysaccharide (DAP), and glucans from yeast (G-Y) and barley (G-B), were investigated in vitro for their intestinal-promoting functions such as inhibition of digestive enzymes, effect of blood glucose and blood lipid levels by using ultraviolet spectrophotometry, as well as the relationship of their structures to those functions. The results indicated that all polysaccharides significantly slowed glucose diffusion rate, decreased protease, and pancreatic lipase activities. Increased branching degrees had a deleterious effect on the α-amylase activity but increased bile acid binding. Increased calcium concentration in glucans (G-Y and G-B) and increased mannose molar ratio in Dendrobium polysaccharides (DOP and DAP) were correlated with increased pancreatic lipase inhibition. The polysaccharides with higher glucose content and branching degrees had higher bile acid binding and disruption of cholesterol micelle formation. These polysaccharides exerted a variety of potential health-promoting effects attributed to their different structures, which should be further investigated in vivo.
- Subjects :
- cholesterol micelle
lcsh:TX341-641
Polysaccharide
01 natural sciences
Dendrobium
Dendrobium officinale
0404 agricultural biotechnology
Pancreatic lipase
chemistry.chemical_classification
bile acids
biology
lcsh:TP368-456
010401 analytical chemistry
04 agricultural and veterinary sciences
biology.organism_classification
040401 food science
In vitro
0104 chemical sciences
intestinal function
lcsh:Food processing and manufacture
dendrobium
chemistry
Biochemistry
pancreatic lipase
biology.protein
lcsh:Nutrition. Foods and food supply
Function (biology)
β-d-glucans
Food Science
Subjects
Details
- Language :
- English
- ISSN :
- 15322386 and 10942912
- Volume :
- 22
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- International Journal of Food Properties
- Accession number :
- edsair.doi.dedup.....f0e66d2758ff7353ebf2068e8f3ddd2d