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Mechanically switchable solid inhomogeneous phantom for performance tests in diffuse imaging and spectroscopy
- Source :
- Journal of biomedical optics 20 (2015). doi:10.1117/1.JBO.20.12.121304, info:cnr-pdr/source/autori:Pifferi, Antonio; Torricelli, Alessandro; Cubeddu, Rinaldo; Quarto, Giovanna; Re, Rebecca; Sekar, Sanathana K. V.; Spinelli, Lorenzo; Farina, Andrea; Martelli, Fabrizio; Wabnitz, Heidrun/titolo:Mechanically switchable solid inhomogeneous phantom for performance tests in diffuse imaging and spectroscopy/doi:10.1117%2F1.JBO.20.12.121304/rivista:Journal of biomedical optics/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume:20
- Publication Year :
- 2015
- Publisher :
- International Biomedical Optics Society., Bellingham, WA, 2015.
-
Abstract
- A mechanically switchable solid inhomogeneous phantom simulating localized absorption changes was developed and characterized. The homogeneous host phantom was made of epoxy resin with black toner and titanium dioxide particles added as absorbing and scattering components, respectively. A cylindrical rod, movable along a hole in the block and made of the same material, has a black polyvinyl chloride cylinder embedded in its center. By varying the volume and position of the black inclusion, absorption perturbations can be generated over a large range of magnitudes. The phantom has been characterized by various timedomain diffuse optics instruments in terms of absorption and scattering spectra, transmittance images, and reflectance contrast. Addressing a major application of the phantom for performance characterization for functional near-infrared spectroscopy of the brain, the contrast was measured in reflectance mode while black cylinders of volumes from approximate to 20 mm(3) to approximate to 270 mm(3) were moved in lateral and depth directions, respectively. The new type of solid inhomogeneous phantom is expected to become a useful tool for routine quality check of clinical instruments or implementation of industrial standards provided an experimental characterization of the phantom is performed in advance. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.
- Subjects :
- diffuse optical imaging
diffuse optics
performance characterization
tissue-like phantoms
Biomedical Engineering
Biomaterials
Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Materials science
Sensitivity and Specificity
Imaging phantom
Optics
Atomic and Molecular Physics
Image Interpretation, Computer-Assisted
Electronic
Transmittance
Cylinder
Optical and Magnetic Materials
Spectroscopy
Absorption (electromagnetic radiation)
Phantoms, Imaging
Scattering
business.industry
Spectrum Analysis
Optical Imaging
Near-infrared spectroscopy
Reproducibility of Results
Equipment Design
Diffuse optical imaging
Molecular Imaging
Equipment Failure Analysis
and Optics
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Journal of biomedical optics 20 (2015). doi:10.1117/1.JBO.20.12.121304, info:cnr-pdr/source/autori:Pifferi, Antonio; Torricelli, Alessandro; Cubeddu, Rinaldo; Quarto, Giovanna; Re, Rebecca; Sekar, Sanathana K. V.; Spinelli, Lorenzo; Farina, Andrea; Martelli, Fabrizio; Wabnitz, Heidrun/titolo:Mechanically switchable solid inhomogeneous phantom for performance tests in diffuse imaging and spectroscopy/doi:10.1117%2F1.JBO.20.12.121304/rivista:Journal of biomedical optics/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume:20
- Accession number :
- edsair.doi.dedup.....f0d9cd654cbd98c567c2914cacd53678