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Tyrosine Kinase Inhibitors Display Potent Activity against Cryptosporidium parvum

Authors :
Maria G. Nava
Félix Calderón
Elena Fernández
Lluis Ballell
Paul Bamborough
Sumiti Vinayak
Source :
Microbiology Spectrum. 11
Publication Year :
2023
Publisher :
American Society for Microbiology, 2023.

Abstract

The intestinal parasite Cryptosporidium parvum is a major cause of diarrhea-associated morbidity and mortality in children, immunocompromised people, and young ruminant animals. With no effective drug available to treat cryptosporidiosis in humans and animals, there is an urgent need to identify anti-parasitic compounds and new targets for drug development.

Details

ISSN :
21650497
Volume :
11
Database :
OpenAIRE
Journal :
Microbiology Spectrum
Accession number :
edsair.doi.dedup.....f095e7a890f2457ef806315b98cad0da
Full Text :
https://doi.org/10.1128/spectrum.03874-22