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Multifractal dimension and lacunarity of yolk sac vasculature after exposure to magnetic field
- Source :
- Microvascular research. 99
- Publication Year :
- 2014
-
Abstract
- Several studies have reported about the effects of magnetic fields (MFs) on vascular tissue. Extremely low frequency magnetic fields (ELF-MFs) can promote either inhibition or stimulation of vasculogenesis and angiogenesis, depending upon the intensity and time of exposure to the MF. To investigate the possible effects of ELF-MF on vascular processes, it is necessary to employ methods that allow parameterization of the vascular network. Vascular network is a structure with fractal geometry; therefore, fractal methods have been used to evaluate its morphometric complexity. Here, we used the lacunarity parameter (complementary method of fractal analysis) and multifractal analyses to investigate angiogenesis and vasculogenesis in the embryonic yolk sac membrane (YSM) of Japanese quails (Coturnix japonica) with and without exposure to an external MF of 1 mT and 60 Hz. Lacunarity results showed that the vascular density was lower for the group exposed to the magnetic field for 9 h/day. In addition, multifractal analysis showed reduced vascularization in the experimental groups (6 h/day and 9 h/day of exposure to MF). Furthermore, multifractal analysis showed difference between the groups exposed for 12 and 24 h/day. Using multifractal methods (generalized dimensions and singularity spectrum), it was possible to characterize the vascular network of the quail embryo YSM as a multifractal object, therefore proving this method to be a more appropriate application than the traditional monofractal methods.
- Subjects :
- Radiation, Nonionizing
Embryo, Nonmammalian
Time Factors
Coturnix
Biochemistry
Fractal
Vasculogenesis
Lacunarity
medicine
Animals
Yolk sac
Singularity spectrum
Vascular tissue
Probability
Yolk Sac
Models, Statistical
Neovascularization, Pathologic
Chemistry
Cell Biology
Anatomy
Multifractal system
Fractal analysis
medicine.anatomical_structure
Fractals
Magnetic Fields
Blood Vessels
Cardiology and Cardiovascular Medicine
Biomedical engineering
Subjects
Details
- ISSN :
- 10959319
- Volume :
- 99
- Database :
- OpenAIRE
- Journal :
- Microvascular research
- Accession number :
- edsair.doi.dedup.....f06909fa6c5abcaacba5db8f5d75514d