A Kelch domain-containing KLHDC7B and a long non-coding RNA ST8SIA6-AS1 act oppositely on breast cancer cell proliferation via the interferon signaling pathway

Authors :: Sungbin Park
Hansol Bae
Han-Sung Kang
Gookjoo Jeong
Hyeon Woo Kim
Juyeon Ham
Sun Jung Kim
Dawoon Jeong
Source :: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018), Scientific Reports
Publication Year :: 2018
Publisher :: Springer Science and Business Media LLC, 2018.
Abstract: In our previous study, the Kelch domain-containing 7B (KLHDC7B) was revealed to be hypermethylated at the promoter but upregulated in breast cancer. In this study, we identified a long non-coding RNA, ST8SIA6-AS1 (STAR1), whose expression was significantly associated with KLHDC7B in breast cancer (R2 = 0.3466, P

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