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The orchestrated signaling by PI3Kα and PTEN at the membrane interface

Authors :
Danai Maria Kotzampasi
Kyriaki Premeti
Alexandra Papafotika
Vasiliki Syropoulou
Savvas Christoforidis
Zoe Cournia
George Leondaritis
Source :
Computational and structural biotechnology journal. 20
Publication Year :
2022

Abstract

The oncogene PI3Kα and the tumor suppressor PTEN represent two antagonistic enzymatic activities that regulate the interconversion of the phosphoinositide lipids PI(4,5)P

Subjects

Subjects :
Structural Biology
Genetics
Biophysics
Biochemistry
Computer Science Applications
Biotechnology

Details

ISSN :
20010370
Volume :
20
Database :
OpenAIRE
Journal :
Computational and structural biotechnology journal
Accession number :
edsair.doi.dedup.....f04ad34a441db52505fa896dc8c44e84

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