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The immunity regulator BAK1 contributes to resistance against diverse RNA viruses
- Source :
- Molecular Plant-Microbe Interactions, Molecular Plant-Microbe Interactions, American Phytopathological Society, 2013, 26 (11), pp.1271-1280, MOLECULAR PLANT-MICROBE INTERACTIONS
- Publication Year :
- 2013
-
Abstract
- The plant's innate immune system detects potential biotic threats through recognition of microbe-associated molecular patterns (MAMPs) or danger-associated molecular patterns (DAMPs) by pattern recognition receptors (PRR). A central regulator of pattern-triggered immunity (PTI) is the BRI1-associated kinase 1 (BAK1), which undergoes complex formation with PRR upon ligand binding. Although viral patterns inducing PTI are well known from animal systems, nothing similar has been reported for plants. Rather, antiviral defense in plants is thought to be mediated by post-transcriptional gene silencing of viral RNA or through effector-triggered immunity, i.e., recognition of virus-specific effectors by resistance proteins. Nevertheless, infection by compatible viruses can also lead to the induction of defense gene expression, indicating that plants may also recognize viruses through PTI. Here, we show that PTI, or at least the presence of the regulator BAK1, is important for antiviral defense of Arabidopsis plants. Arabidopsis bak1 mutants show increased susceptibility to three different RNA viruses during compatible interactions. Furthermore, crude viral extracts but not purified virions induce several PTI marker responses in a BAK1-dependent manner. Overall, we conclude that BAK1-dependent PTI contributes to antiviral resistance in plants.
- Subjects :
- 0106 biological sciences
Physiology
Arabidopsis
[SDV.BC]Life Sciences [q-bio]/Cellular Biology
Protein Serine-Threonine Kinases
01 natural sciences
Plant Roots
Plant Viruses
03 medical and health sciences
Plant Growth Regulators
RNA interference
Gene expression
Gene silencing
RNA Viruses
Plant Immunity
ComputingMilieux_MISCELLANEOUS
030304 developmental biology
Plant Diseases
0303 health sciences
Innate immune system
biology
Effector
Arabidopsis Proteins
fungi
Pattern recognition receptor
Virion
food and beverages
RNA
[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology
General Medicine
Ethylenes
biology.organism_classification
Virology
Cell biology
Seedlings
Receptors, Pattern Recognition
Host-Pathogen Interactions
Mutation
RNA, Viral
RNA Interference
Agronomy and Crop Science
010606 plant biology & botany
Protein Binding
Signal Transduction
Subjects
Details
- ISSN :
- 08940282
- Volume :
- 26
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Molecular plant-microbe interactions : MPMI
- Accession number :
- edsair.doi.dedup.....f0407c86c087515b21fea358c530bdd9