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Histological and Ultrastructural Description of Benign Adipocytic Tumors in Farmed Striped Sea Bream (Lythognathus mormyrus)
- Source :
- Animals, Vol 11, Iss 3413, p 3413 (2021), Animals; Volume 11; Issue 12; Pages: 3413
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Cutaneous neoplasms affecting wild striped bream (Lythognathus mormyrus) have been recorded after their introduction in a marine aquaculture farm in the Adriatic Sea. The tumors were evident on 24% of the reared fish, showing single or multiple nodules, with a diameter ranging between 0.5–4.0 cm. Histologically, all the neoplastic lesions were located in the stratum spongiosum of the dermis and were surrounded by a thin capsule of connective tissue. The tumors were predominantly composed of adipocytes grouped and surrounded by a thin net of fibroblasts and collagen fibers. In some lipomas a mixture of adipocytes and uniform spindle cells were also observed. Fibroblasts and collagen fibers, or spindle cells, showing few mitotic figures were mainly observed in other nodules. Three of the tumors showed bands of cells with elongated nuclei. Five neoplasms differed from the classic spindle cell lipoma due to the presence of scattered giant cells. These cells presented acidophilic abundant cytoplasm with multiple hyperchromatic nuclei showing a concentric “floret-like” arrangement. The tumors were further characterized by ultrastructural observations that allowed ruling out the presence of virus-like particles within the lesions. Histological features of the masses lead to the identification of four prevalent patterns of neoplasms: lipoma, fibrolipoma, spindle cell lipoma (SCL), and atypical spindle cell-like lipoma (ASCL). The different neoplasms could arise from the transformation of mesenchymal cells of dermal origin. To the author’s knowledge, this is the first report describing key differential histological and ultrastructural features of these neoplasms in striped sea bream.
- Subjects :
- tumors
Pathology
medicine.medical_specialty
Veterinary medicine
lipoma
Connective tissue
Biology
Dermis
SF600-1100
medicine
atypical spindle cell-like lipoma
Fibrolipoma
General Veterinary
Mesenchymal stem cell
striped sea bream
Lipoma
fibrolipoma
medicine.disease
stomatognathic diseases
medicine.anatomical_structure
QL1-991
spindle cell lipoma
Giant cell
Spindle cell lipoma
Ultrastructure
Animal Science and Zoology
Zoology
Subjects
Details
- Language :
- English
- ISSN :
- 20762615
- Volume :
- 11
- Issue :
- 3413
- Database :
- OpenAIRE
- Journal :
- Animals
- Accession number :
- edsair.doi.dedup.....effdaff52efe9272717b9250e1ed3e4e