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Inherited Neurodegenerative Disorders Caused by CAG/Polyglutamine Tract Expansions: Symposium Introduction
- Source :
- Brain Pathol
- Publication Year :
- 1997
- Publisher :
- Wiley, 1997.
-
Abstract
- At the beginning of this decade, the American Association of Neurology decided that the 1990's should be labelled “the decade of the brain” for expected advances in our understanding of neurological disorders and neuroscience. By the end of this decade, clinicians and researchers who work in the field of inherited neurological disorders might well remember the 1990's as “the decade of the trinucleotide repeat”. At the time of writing this introduction, eleven inherited neurological disorders have been found to be caused by expansions of trinucleotide repeats, and a twelfth trinucleotide repeat expansion mutation has been identified (6), although the gene containing this mutant triplet repeat has not been cloned to our knowledge (Table 1).
- Subjects :
- Genetics
medicine.medical_specialty
Symposium
Neurology
General Neuroscience
Triplet repeat
Polyglutamine tract
Biology
Decade of the Brain
Pathology and Forensic Medicine
Muscular Atrophy, Spinal
Muscular Atrophy
Huntington Disease
Trinucleotide Repeats
Friedreich Ataxia
Fragile X Syndrome
Nerve Degeneration
medicine
Humans
Myotonic Dystrophy
Neurology (clinical)
Peptides
Trinucleotide repeat expansion
Spinocerebellar Degenerations
Subjects
Details
- ISSN :
- 17503639 and 10156305
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Brain Pathology
- Accession number :
- edsair.doi.dedup.....efd3bf03370b196f6c793016c6bcc24d