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Impact of CPAP on forehead near-infrared spectroscopy measurements in patients with acute respiratory failure: truth or illusion
- Publication Year :
- 2019
-
Abstract
- BACKGROUND Critically ill patients with acute respiratory failure admitted to an intensive care unit are at high risk for cerebral hypoxia. We investigated the impact of continuous positive airway pressure (CPAP) therapy on regional cerebral tissue oxygenation (rSO2). MATERIALS AND METHODS In total, 40 extubated surgical intensive care unit patients requiring classic oxygen therapy (COT) for acute respiratory failure were examined. Near-infrared spectroscopy (INVOS 5100C, Covidien) was used for 30 minutes to detect bilateral rSO2 during COT via facemask (6 L/min) and CPAP therapy (40% fraction of inspired oxygen, 8 cm H2O CPAP) using a randomized crossover study design. Patients served as their own control. Continuous hemodynamic routine monitoring and blood gas analysis were performed. The effect of CPAP therapy on rSO2 and influence of assessed covariables were investigated using a mixed linear model. RESULTS Median rSO2 increased from 57.9% (95% confidence interval [CI], 54.2-61.5) during COT to 62.8% (95% CI, 59.2-66.5) during CPAP therapy (P
- Subjects :
- Adult
Male
Critical Care
Critical Illness
medicine.medical_treatment
Hemodynamics
law.invention
03 medical and health sciences
0302 clinical medicine
030202 anesthesiology
law
Fraction of inspired oxygen
Oxygen therapy
Humans
Medicine
Forehead
Continuous positive airway pressure
Hypoxia, Brain
Aged
Monitoring, Physiologic
Aged, 80 and over
Cross-Over Studies
Spectroscopy, Near-Infrared
Continuous Positive Airway Pressure
business.industry
Cerebral hypoxia
Oxygenation
Middle Aged
Hypoxia (medical)
medicine.disease
Intensive care unit
respiratory tract diseases
Oxygen
Anesthesiology and Pain Medicine
Anesthesia
Female
Surgery
Neurology (clinical)
Blood Gas Analysis
medicine.symptom
Respiratory Insufficiency
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....efc418170eaf2d512686fbaff5348046