A Serum Level of Squamous Cell Carcinoma Antigen as a Real-Time Biomarker of Atopic Dermatitis

Background: Although serum levels of squamous cell carcinoma antigen (SCCA) are elevated in atopic dermatitis (AD), their clinical utility has not been fully elucidated. Methods: Thirty-three cases of AD who admitted to our hospital were analyzed. Results: Baseline characteristics on admission were as follows: median age 19 months [interquartile range (IQR), 12–52 months], median objective severity scoring of atopic dermatitis (O-SCORAD) 19.2 (IQR, 4.2–36.0), and median serum SCCA levels 3.2 ng/mL (IQR, 2.1–6.8 ng/mL). O-SCORAD significantly correlated with serum SCCA levels (rs = 0.865, P