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Selective nickel-catalyzed fluoroalkylations of olefins
- Source :
- Chemical Communications. 56:15157-15160
- Publication Year :
- 2020
- Publisher :
- Royal Society of Chemistry (RSC), 2020.
-
Abstract
- Mild and selective nickel-catalyzed trifluoromethylation and perfluoroalkylation reactions of alkenes were developed to provide fluorinated olefins, including natural products, pharmaceuticals, and variety of synthetic building blocks in good to excellent yields (38 examples). Control experiments, kinetic measurements and in situ EPR studies reveal the importance of radical species and the formation of 1,2-adducts as intermediates.
- Subjects :
- Chemistry
Trifluoromethylation
Metals and Alloys
chemistry.chemical_element
General Chemistry
Combinatorial chemistry
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
law.invention
Nickel
law
Materials Chemistry
Ceramics and Composites
Electron paramagnetic resonance
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....ef7de7fb6b0688b5502d3c4b3711d1e3