Back to Search
Start Over
Cytopathologic Features of Secretory Carcinoma of Salivary Gland: Report of Two Cases
- Source :
- Journal of Pathology and Translational Medicine, Vol 53, Iss 1, Pp 70-74 (2019), Journal of Pathology and Translational Medicine
- Publication Year :
- 2019
- Publisher :
- Korean Society of Pathologists & the Korean Society for Cytopathology, 2019.
-
Abstract
- Secretory carcinoma of the salivary gland (SC) is a newly introduced rare salivary gland tumor that shares histological, immunohistochemical, and genetic characteristics with secretory carcinoma of the breast. Here, we report the cytologic features of two cases of SC confirmed by surgical resection. In these two cases, SC was incidentally detected in a 64-year-old female and a 56-yearold male. Fine needle aspiration cytology revealed nests of tumor cells with a papillary or glandular structure floating in mucinous secretions. The tumor cells demonstrated uniform, round, smooth nuclear contours and distinct nucleoli. Multiple characteristic cytoplasmic vacuoles were revealed. Singly scattered tumor cells frequently showed variable sized cytoplasmic vacuoles. The cytopathologic diagnosis of SC should be considered when characteristic cytological findings are revealed. Further immunohistochemistry and gene analyses are helpful to diagnose SC.
- Subjects :
- 0301 basic medicine
Pathology
medicine.medical_specialty
Mammary analogue secretory carcinoma
Histology
Nucleolus
Vacuole
Pathology and Forensic Medicine
03 medical and health sciences
0302 clinical medicine
Fine needle aspiration cytology
Cytology
medicine
lcsh:Pathology
Salivary gland
Secretory carcinoma
Case Study
business.industry
Secretory Carcinoma
030104 developmental biology
medicine.anatomical_structure
Cytoplasm
030220 oncology & carcinogenesis
Immunohistochemistry
business
lcsh:RB1-214
Subjects
Details
- Language :
- English
- ISSN :
- 23837845 and 23837837
- Volume :
- 53
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Pathology and Translational Medicine
- Accession number :
- edsair.doi.dedup.....ef67814272359820d2c071c11d14c7bf