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Synthesis andin vitro cytotoxicity of 1-azaanthraquinone-3-carboxamides
- Source :
- Archives of Pharmacal Research. 22:380-383
- Publication Year :
- 1999
- Publisher :
- Springer Science and Business Media LLC, 1999.
-
Abstract
- Five 1-azaanthraquinone-3-carboxamides were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines. The most active compound, 7b, exhibited cytotoxic activity comparable to doxorubicin.
- Subjects :
- Chemotherapy
Antibiotics, Antineoplastic
Chemistry
medicine.medical_treatment
Organic Chemistry
Anthraquinones
Cell Count
Drug resistance
Pharmacology
Amides
In vitro
Doxorubicin
Cell culture
Active compound
Drug Discovery
Tumor Cells, Cultured
medicine
Humans
Molecular Medicine
Cytotoxic T cell
Cytotoxicity
medicine.drug
Subjects
Details
- ISSN :
- 19763786 and 02536269
- Volume :
- 22
- Database :
- OpenAIRE
- Journal :
- Archives of Pharmacal Research
- Accession number :
- edsair.doi.dedup.....ef5ed9b50390914a7a9f9da168e46308
- Full Text :
- https://doi.org/10.1007/bf02979061