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Predictors of All-Cause Mortality after Endovascular Aneurysm Repair: Assessing the Role of Psoas Muscle Cross-Sectional Area
- Source :
- Journal of Vascular and Interventional Radiology. 30:1972-1979
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Purpose To evaluate psoas muscle area (PMA) as a predictor of all-cause mortality after endovascular aneurysm repair (EVAR) and compare it with other predictor variables. Material and Methods Retrospective review of 407 patients who underwent EVAR over a 7-year period was performed. Demographics, comorbidity variables, and outcomes were collected. Preprocedure computed tomography scans were used to measure the PMA. Descriptive statistics summarized the demographic information and predictor variables. Kaplan-Meier analysis and univariate and multivariate Cox proportional regression analyses were performed. The main outcome measure was survival time. Results Median survival time for patients with PMA in the lowest quartile of the distribution (≤1442 mm2) was 65.5 months (95% confidence interval [95% CI] 37.7–78.9) vs 91.2 months (95% CI 77.9–110.0 when PMA >1442 mm2). Multivariate analysis revealed lower PMA was associated with decreased survival (adjusted hazard ratio [AHR] 1.68; 95% CI 1.15–2.40, P = .006). Similarly, the presence of coronary artery disease (AHR 1.54, 95% CI 1.01–2.35, P = .045) and statin use after EVAR were associated with decreased survival (AHR 2.36, 95% CI 1.24–4.49, P = .009). Hyperlipidemia was associated with increased survival after EVAR (AHR 0.51, 95% CI 0.33–0.81, P = .004). Compared with patients with low body mass index (BMI) ( Conclusions Although PMA is a risk factor for decreased survival time, other factors such as patient hyperlipidemia, presence of coronary artery disease, post-EVAR statin use, and BMI are also predictive of postoperative mortality.
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Hyperlipidemias
Coronary Artery Disease
Risk Assessment
Endovascular aneurysm repair
Body Mass Index
030218 nuclear medicine & medical imaging
Coronary artery disease
Blood Vessel Prosthesis Implantation
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Risk Factors
Cause of Death
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Risk factor
Aged
Psoas Muscles
Retrospective Studies
Aged, 80 and over
business.industry
Endovascular Procedures
Hazard ratio
Middle Aged
medicine.disease
Confidence interval
Aortic Aneurysm
Treatment Outcome
Quartile
030220 oncology & carcinogenesis
Predictive value of tests
Female
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Tomography, X-Ray Computed
Cardiology and Cardiovascular Medicine
business
Body mass index
Subjects
Details
- ISSN :
- 10510443
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Journal of Vascular and Interventional Radiology
- Accession number :
- edsair.doi.dedup.....eefc781a8feea195e8b29de90c930a7f
- Full Text :
- https://doi.org/10.1016/j.jvir.2019.04.032