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Comparison of the rate of refractive growth in aphakic eyes versus pseudophakic eyes in the Infant Aphakia Treatment Study
- Source :
- Journal of cataract and refractive surgery. 42(12)
- Publication Year :
- 2016
-
Abstract
- Purpose To compare the rate of refractive growth (RRG) between aphakic eyes and pseudophakic eyes in the Infant Aphakia Treatment Study (IATS). Setting Twelve clinical sites across the United States. Design Randomized clinical trial. Methods Patients randomized to unilateral cataract extraction with contact lens correction versus intraocular lens (IOL) implantation in the IATS had their rate of refractive growth (RRG3) calculated based on the change in refraction from the 1-month postoperative examination to age 5 years. The RRG3 is a logarithmic formula designed to calculate the RRG in children. Two-group t tests were used to compare the mean refractive growth between the contact lens group and IOL group and outcomes based on age at surgery and visual acuity. Results Longitudinal refractive data were studied for 108 of 114 patients enrolled in the IATS (contact lens group, n = 54; IOL group, n = 54). The mean RRG3 was similar in the contact lens group (−18.0 diopter [D] ± 11.0 [SD]) and the IOL group (−19.0 ± 9.0 D) ( P = .49). The RRG3 value was not correlated with age at cataract surgery, glaucoma status, or visual outcome in the IOL group. In the aphakia group, only visual outcome was correlated with refractive growth ( P = .01). Conclusions Infants' eyes had a similar rate of refractive growth after unilateral cataract surgery whether or not an IOL was implanted. A worse visual outcome was associated with a higher RRG in aphakic, but not pseudophakic, eyes. Financial Disclosure None of the authors has a financial or proprietary interest in any material or method mentioned.
- Subjects :
- medicine.medical_specialty
Visual acuity
genetic structures
medicine.medical_treatment
Visual Acuity
Glaucoma
Intraocular lens
Aphakia, Postcataract
Cataract Extraction
Aphakia
Cataract
Article
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
Lens Implantation, Intraocular
law
Ophthalmology
medicine
Humans
030212 general & internal medicine
Dioptre
Retrospective Studies
Lenses, Intraocular
business.industry
Infant
Cataract surgery
medicine.disease
eye diseases
Sensory Systems
Contact lens
030221 ophthalmology & optometry
Surgery
sense organs
medicine.symptom
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 18734502
- Volume :
- 42
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Journal of cataract and refractive surgery
- Accession number :
- edsair.doi.dedup.....eebf8f4f0268a20a048456eb4c95eb84