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Allelic Antigenic Factor Inv(a) of the Light Chains of Human Immunoglobulins: Chemical Basis
- Source :
- Science. 152:1517-1519
- Publication Year :
- 1966
- Publisher :
- American Association for the Advancement of Science (AAAS), 1966.
-
Abstract
- Twenty-seven Bence Jones proteins of immunological type K show a common set of peptides. One 6f the commnon peptides differs in three of the proteins which are the only ones classified by a serological test as Iav(a+). The difference in the peptide analyzed is caused by a valine-leucine interchange; Inv(a+) proteins have leucine, whereas Inv(a-) proteins have valine in position 189.
- Subjects :
- Electrophoresis
chemistry.chemical_classification
Multidisciplinary
Chromatography, Paper
Peptide
In Vitro Techniques
biochemical phenomena, metabolism, and nutrition
Biology
Immunoglobulin light chain
Molecular biology
Bence Jones protein
Paper chromatography
chemistry
Biochemistry
Antigen
Valine
Blood Group Antigens
Chromatography, Gel
Humans
Amino Acid Sequence
Leucine
Peptides
Peptide sequence
Bence Jones Protein
Subjects
Details
- ISSN :
- 10959203 and 00368075
- Volume :
- 152
- Database :
- OpenAIRE
- Journal :
- Science
- Accession number :
- edsair.doi.dedup.....ee555f9e93e0d512976890e5a5486be2