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New-onset ventricular arrhythmias post radiofrequency catheter ablation for atrial fibrillation
- Source :
- Medicine
- Publication Year :
- 2016
- Publisher :
- Wolters Kluwer Health, 2016.
-
Abstract
- As a new complication, new-onset ventricular arrhythmias (VAs) post atrial fibrillation (AF) ablation have not been well defined. This prospective study aimed to describe the details of new-onset VAs post AF ablation in a large study cohort. One thousand fifty-three consecutive patients who underwent the first radiofrequency catheter ablation for AF were enrolled. All patients had no evidence of pre-ablation VAs. New-onset VAs were defined as new-onset ventricular tachycardia (VT) or premature ventricular contractions (PVC) ≥1000/24 h within 1 month post ablation. There were 46 patients (4.4%) who had 62 different new-onset VAs, among whom 42 were PVC alone, and 4 were PVC coexisting with nonsustained VT. Multivariate analysis showed that increased serum leukocyte counts ≥50% post ablation were independently associated with new-onset VAs (OR: 1.9; 95% CI: 1.0–3.5; P = 0.043). The median number of PVC was 3161 (1001–27,407) times/24 h. Outflow tract VAs were recorded in 35 (76.1%) patients. No significant differences were found in origin of VAs (P = 0.187). VAs disappeared without any treatment in 6 patients (13.0%). No VAs-related adverse cardiac event occurred. The study revealed a noticeable prevalence but relatively benign prognosis of new-onset VAs post AF ablation. Increased serum leukocyte counts ≥50% post ablation appeared to be associated with new-onset VAs, implying that inflammatory response caused by ablation might be the mechanism.
- Subjects :
- Adult
Male
medicine.medical_specialty
China
medicine.medical_treatment
Observational Study
radiofrequency catheter ablation
030204 cardiovascular system & hematology
New onset
03 medical and health sciences
0302 clinical medicine
Postoperative Complications
Internal medicine
Atrial Fibrillation
medicine
Prevalence
Humans
cardiovascular diseases
030212 general & internal medicine
Prospective Studies
Prospective cohort study
ventricular arrhythmia
Aged
business.industry
Atrial fibrillation
Arrhythmias, Cardiac
General Medicine
Middle Aged
Ablation
medicine.disease
Surgery
Radiofrequency catheter ablation
inflammation
cardiovascular system
Large study
Cardiology
Catheter Ablation
Female
business
Complication
Af ablation
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 15365964 and 00257974
- Volume :
- 95
- Issue :
- 36
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.doi.dedup.....ee4fb5436e8a5379d7753ce2c193142d