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Multiplexing and multivariate analysis in neurodegeneration
- Source :
- Methods. 56:464-470
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- Limited sample volume is often an obstacle in clinical research and one way to circumvent this is to use multiplex techniques where several different analytes are simultaneously measured. There is a multitude of different platforms that can be used for multiplexing and their uniqueness and similarities will be described. Multivariate analysis is a powerful tool for extracting information from multiplex data. An introduction to one such algorithm is presented followed by examples from the literature, in the field of neurodegeneration, where multiplex and multivariate methods have been used.
- Subjects :
- Multivariate statistics
Multivariate analysis
Protein Array Analysis
Enzyme-Linked Immunosorbent Assay
Neurodegenerative Diseases
Biology
computer.software_genre
Bioinformatics
Multiplexing
Mass Spectrometry
Microspheres
General Biochemistry, Genetics and Molecular Biology
Field (computer science)
Microsphere
Sample volume
Multivariate Analysis
Metabolome
Humans
Multiplex
Data mining
Molecular Biology
computer
Algorithms
Biomarkers
Subjects
Details
- ISSN :
- 10462023
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Methods
- Accession number :
- edsair.doi.dedup.....ee3f5e5248b16994caae3934c71abd08