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Effects of denture adhesives on growth and morphological transformation of Candida albicans
- Source :
- Journal of prosthodontic research. 64(1)
- Publication Year :
- 2018
-
Abstract
- Purpose We investigated the effects of denture adhesives (cream (Cr), powder (Po), and cushion (Cu)) on growth and adhesive-related morphological transformation of Candida albicans. For this purpose, the numbers of adherent C. albicans, hyphae-specific gene expressions, and the SEM images were examined. Methods Acrylic resin blocks were prepared as controls (Co). Cr, Po, and Cu were thinly spread on the surface of the resin block.C. albicans suspension was seeded on the specimens and incubated at 4 °C for 2 h. The numbers of C. albicans adhering to each specimen at each incubation time period (1, 2, 3, 6, 12, and 24 h) were quantified using real-time RT-PCR. The hyphae-specific genes expressions were examined. The surface of each specimen was observed under the SEM to detect the transformation to the hyphal form. Results The initial adhesion rates in all groups were not statistically significant. The numbers of C. albicans adhering increased with time in all groups, and those adhering to the Cr, Po, and Cu were significantly greater than that adhering to the Co. In the Cr and Po, the hyphal-specific genes expressions were higher after incubation for 6 h. The transformation to the hyphal form was identified in the Cr and Po after incubation for 6 and 12 h. Conclusions The denture adhesives used in this study accelerated the growth of C. albicans. Moreover, the early transformation to the hyphal form on the Cr- and Po-type adhesives was observed, suggesting that we should carefully use Cr- and Po-type adhesives.
- Subjects :
- Denture Bases
Hypha
0206 medical engineering
Acrylic Resins
Dental Cements
02 engineering and technology
Incubation period
03 medical and health sciences
0302 clinical medicine
Candida albicans
Dentistry (miscellaneous)
Acrylic resin
Incubation
biology
Chemistry
030206 dentistry
Adhesion
biology.organism_classification
020601 biomedical engineering
Corpus albicans
visual_art
Biofilms
visual_art.visual_art_medium
Adhesive
Oral Surgery
Nuclear chemistry
Subjects
Details
- ISSN :
- 22124632
- Volume :
- 64
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of prosthodontic research
- Accession number :
- edsair.doi.dedup.....ee1bb92728e8c8694d68d78a15b84d7c