Clinical Evaluation of a Radioimmunoprecipitation Assay for IA-2 Antibody and Comparison of GAD Antibody in Type 1 Diabetes Mellitus

Authors :: Michiaki Fukui
Nobuyuki Itoh
Kiyoe Ohta
Masataka Nishimura
Naoto Nakamura
Hirofumi Shigeta
Yoshihiro Kitagawa
Koji Nakano
Mitsuhiro Ohta
Goji Hasegawa
Hiroshi Obayashi
Source :: Autoimmunity. 32:79-88
Publication Year :: 2000
Publisher :: Informa UK Limited, 2000.
Abstract: We evaluated a insulinoma-associated protein (IA-2) antibody assay kit using 125I-labelled recombinant IA-2. IA-2 antibodies were present in patients with early-onset type 1 diabetes mellitus (DM) at frequencies of 74%, 67%, 57%, and 50% for respective periods

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