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Environmental risk factors and male fertility and reproduction
- Source :
- Contraception. 65(4)
- Publication Year :
- 2002
-
Abstract
- Several environmental substances and pesticides exert a direct, cytotoxic effect on male germ cells. However, an increasing concern has been raised by compounds that may act through more subtle mechanisms, for example, specific pesticides that are potentially capable of modulating or disrupting the endocrine system. Overall, exposure to pesticides with endocrine-disrupting potential raise a particular concern for male fertility because of the possible occurrence of both effects at low concentrations and additive interactions with other environmental risk factors. Delayed reproductive problems deserve special attention, since experimental data consistently indicate a high vulnerability in the developing male reproductive system. Epidemiologic studies have confirmed an increased risk of conception delay associated with occupational exposure to pesticides. Moreover, an increased risk of spontaneous abortion has been noted among wives of exposed workers.
- Subjects :
- Male
medicine.medical_specialty
media_common.quotation_subject
Fertility
Biology
Abortion
Occupational medicine
Risk Factors
Internal medicine
Environmental health
Occupational Exposure
medicine
Endocrine system
Humans
Risk factor
Pesticides
Infertility, Male
media_common
Reproduction
Obstetrics and Gynecology
Agriculture
Pesticide
Endocrinology
Reproductive Medicine
Endocrine disruptor
Toxicity
Environmental Pollutants
Subjects
Details
- ISSN :
- 00107824
- Volume :
- 65
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Contraception
- Accession number :
- edsair.doi.dedup.....edde01c0be2ff6b7630214f72194ef4b