Coronary computed tomography angiography-based endothelial wall shear stress in normal coronary arteries

Authors :: Schultz, J.
Hoogen, I.J. van den
Kuneman, J.H.
Graaf, M.A. de
Kamperidis, V.
Broersen, A.
Jukema, J.W.
Sakellarios, A.
Nikopoulos, S.
Tsarapatsani, K.
Naka, K.
Michalis, L.
Fotiadis, D.I.
Maaniitty, T.
Saraste, A.
Bax, J.J.
Knuuti, J.
Source :: The International Journal of Cardiovascular Imaging, 39, 441-450. SPRINGER
Publication Year :: 2022
Publisher :: SPRINGER, 2022.
Abstract: Endothelial wall shear stress (ESS) is a biomechanical force which plays a role in the formation and evolution of atherosclerotic lesions. The purpose of this study is to evaluate coronary computed tomography angiography (CCTA)-based ESS in coronary arteries without atherosclerosis, and to assess factors affecting ESS values. CCTA images from patients with suspected coronary artery disease were analyzed to identify coronary arteries without atherosclerosis. Minimal and maximal ESS values were calculated for 3-mm segments. Factors potentially affecting ESS values were examined, including sex, lumen diameter and distance from the ostium. Segments were categorized according to lumen diameter tertiles into small (

Subjects :: Coronary computed tomography angiography
Endothelial wall shear stress
Computational fluid dynamics
Atherosclerosis
Coronary artery disease

Language :: English
Database :: OpenAIRE
Journal :: The International Journal of Cardiovascular Imaging, 39, 441-450. SPRINGER
Accession number :: edsair.doi.dedup.....ed43bf84f9a5a01d3578f8164e4e4acb

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