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Endoscopic Findings in Patients With PTEN Hamartoma Tumor Syndrome Undergoing Surveillance
- Source :
- Journal of Clinical Gastroenterology. 56:e183-e188
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- Goals and Background: Phosphatase and tensin homolog hamartoma tumor syndrome (PHTS) is an inherited disorder that increases the risk for cancer in multiple organ systems, including breast, endometrial, thyroid, and the gastrointestinal tract. Surveillance is recommended however there lacks data to describe the change in polyposis phenotype and cancer incidence over surveillance. Our aim is to describe the polyposis phenotype and cancer incidence in PHTS patients undergoing endoscopic surveillance. Study: PHTS patients, ages 17 through 89, who underwent at least 2 esophagogastroduodenoscopy (EGDs) or colonoscopies were identified. Number and sizes of polyps were noted, from which 5 categories were recreated. Incidence of colorectal and gastric cancer was evaluated. Results: Seventy patients were included. Patients were clustered and classified into 1 of 5 categories: no polyps, few small polyps (
- Subjects :
- medicine.medical_specialty
Colorectal cancer
Colonic Polyps
Colonoscopy
Gastroenterology
Polyps
Internal medicine
otorhinolaryngologic diseases
medicine
Humans
Hamartoma
medicine.diagnostic_test
business.industry
Esophagogastroduodenoscopy
Incidence (epidemiology)
PTEN Phosphohydrolase
Transverse colon
Cancer
medicine.disease
digestive system diseases
Adenocarcinoma
Colorectal Neoplasms
Hamartoma Syndrome, Multiple
business
Subjects
Details
- ISSN :
- 01920790
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Gastroenterology
- Accession number :
- edsair.doi.dedup.....ed41c81587cdd8c9bd80e94389341940