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Panic Disorder and Agoraphobia in OCD patients: Clinical profile and possible treatment implications
- Source :
- Comprehensive Psychiatry, Vol 55, Iss 3, Pp 588-597 (2014), Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual), Universidade de São Paulo (USP), instacron:USP
- Publication Year :
- 2014
- Publisher :
- Elsevier, 2014.
-
Abstract
- Objective Panic Disorder (PD) and agoraphobia (AG) are frequently comorbid with obsessive–compulsive disorder (OCD), but the correlates of these comorbidities in OCD are fairly unknown. The study aims were to: 1) estimate the prevalence of PD with or without AG (PD), AG without panic (AG) and PD and/or AG (PD/AG) in a large clinical sample of OCD patients and 2) compare the characteristics of individuals with and without these comorbid conditions. Method A cross-sectional study with 1001 patients of the Brazilian Research Consortium on Obsessive–Compulsive Spectrum Disorders using several assessment instruments, including the Dimensional Yale–Brown Obsessive–Compulsive Scale and the Structured Clinical Interview for DSM-IV-TR Axis I Disorders. Bivariate analyses were followed by logistic regression models. Results The lifetime prevalence of PD was 15.3% (N = 153), of AG 4.9% (N = 49), and of PD/AG 20.2% (N = 202). After logistic regression, hypochondriasis and specific phobia were common correlates of the three study groups. PD comorbidity was also associated with higher levels of anxiety, having children, major depression, bipolar I, generalized anxiety and posttraumatic stress disorders. Other independent correlates of AG were: dysthymia, bipolar II disorder, social phobia, impulsive–compulsive internet use, bulimia nervosa and binge eating disorder. Patients with PD/AG were also more likely to be married and to present high anxiety, separation anxiety disorder, major depression, impulsive–compulsive internet use, generalized anxiety, posttraumatic stress and binge eating disorders. Conclusions Some distinct correlates were obtained for PD and AG in OCD patients, indicating the need for more specific and tailored treatment strategies for individuals with each of these clinical profiles.
- Subjects :
- Adult
Male
Obsessive-Compulsive Disorder
medicine.medical_specialty
lcsh:RC435-571
Comorbidity
behavioral disciplines and activities
Specific phobia
Young Adult
Bipolar II disorder
Binge-eating disorder
lcsh:Psychiatry
mental disorders
Prevalence
medicine
Humans
Psychiatry
Agoraphobia
AGORAFOBIA
Bulimia nervosa
Mental Disorders
Panic disorder
Separation anxiety disorder
Middle Aged
medicine.disease
Psychiatry and Mental health
Clinical Psychology
Cross-Sectional Studies
Panic Disorder
Anxiety
Female
medicine.symptom
Psychology
Brazil
Clinical psychology
Subjects
Details
- Language :
- English
- Volume :
- 55
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Comprehensive Psychiatry
- Accession number :
- edsair.doi.dedup.....ed324ef94e0493a8c53922c816bad782