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Risk factors for postoperative delirium in patients with triple-branched stent graft implantation
- Source :
- Journal of Cardiothoracic Surgery, Vol 15, Iss 1, Pp 1-8 (2020), Journal of Cardiothoracic Surgery
- Publication Year :
- 2020
- Publisher :
- BMC, 2020.
-
Abstract
- Background Neurological complications is a common complication following novel triple-branched stent graft implantation in patients with Stanford type A aortic dissection (AAD). But the incidence and risk factors of postoperative delirium (POD) are not completely clear. The aim of this study was to investigate the incidence and risk factors of POD after novel triple-branched stent graft implantation. Methods An observational study of AAD patients who underwent novel triple-branched stent graft implantation between January 2017 and July 2019 were followed up after surgery. Patients’ delirium was screened by the Richmond Agitation-Sedation Scale and the Confusion Assessment Method for the intensive care unit from the first day after the operation, lasted 5 days. The risk factors of POD were analyzed by the Cox proportional hazard models. Results A total of 280 AAD patients were enrolled in this research, the incidence of POD was 37.86%. Adjusting for age, body mass index, and mechanical ventilation duration, multivariate Cox regression analysis model revealed that non-manual work (adjusted hazard ratio [AHR] = .554; 95% CI: 0.335–0.915; P = .021), Acute Physiology and Chronic Health Evaluation II (APACHE-II) scores > 20 (AHR = 3.359, 95% CI: 1.707–6.609, P P = .017), and more than two types of analgesics and sedatives were independently associated with POD. Conclusions This study showed that risk factors independently associated with POD were APACHE-II score > 20, hypoxemia, and more types of analgesics and sedatives, and non-manual work was the protective factor. Trial registration This study was retrospectively registered in the Chinese Clinical Trial Registry (Registration number: ChiCTR1900022408; Date: 2019/4/10).
- Subjects :
- Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
medicine.medical_treatment
Aortic dissection
lcsh:Surgery
Triple-branched stent graft implantation
030204 cardiovascular system & hematology
law.invention
lcsh:RD78.3-87.3
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Japan
law
medicine
Humans
030212 general & internal medicine
APACHE
Proportional Hazards Models
Retrospective Studies
Aortic Aneurysm, Thoracic
business.industry
Proportional hazards model
Incidence
Incidence (epidemiology)
Hazard ratio
Postoperative delirium
Delirium
Stent
General Medicine
lcsh:RD1-811
Middle Aged
Intensive care unit
Surgery
Risk factors
Cardiothoracic surgery
lcsh:Anesthesiology
Female
Stents
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Complication
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 17498090
- Volume :
- 15
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Cardiothoracic Surgery
- Accession number :
- edsair.doi.dedup.....ed27c5cb27dedfd9ef04e0845e47117b