Inspection time as a general measure of cognitive impairment following acute opioid exposure

Aims: Inspection Time (IT) is used to assess speed of information processing in a manner that, unlike other cognitive tests,is independent of motor components and reaction time. IT has been utilised to assess a range of disruptions in brain activity and is affected by drugs such as alcohol, but there is no information on the effect of acute opioid administration. We hypothesised that acute opioid administration would produce a concentrationrelated increase in IT comparable to that produced by moderatedoses of alcohol. Refereed/Peer-reviewed