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Partial genotyping at polymorphic markers can improve heritability estimates in sibling groups
- Source :
- Molecular Ecology Resources, Molecular Ecology Resources, Wiley/Blackwell, 2016, 16 (6), pp.1340-1352. ⟨10.1111/1755-0998.12536⟩, Molecular Ecology Resources 6 (16), 1340-1352. (2016)
- Publication Year :
- 2016
- Publisher :
- HAL CCSD, 2016.
-
Abstract
- Agap : équipe GE2pop; Accurate estimates of heritability (h2) are necessary to assess adaptive responses of populations and evolution of fitness-related traits in changing environments. For plants, h2 estimates generally rely on maternal progeny designs, assuming that offspring are either half-sibs or unrelated. However, plant mating systems often depart from half-sib assumptions, this can bias h2 estimates. Here, we investigate how to accurately estimate h2 in non-model species through the analysis of sibling designs with a moderate genotyping effort. We performed simulations to investigate how microsatellite marker information available for only a subset of offspring can improve h2 estimates based on maternal progeny designs in presence of non-random mating, inbreeding in the parental population or maternal effects. We compared the basic family method, considering or not adjustments based on average relatedness coefficients, and methods based on the animal model. The animal model was used with average relatedness information, or with hybrid relatedness information: associating one-generation pedigree and family assumptions, or associating one-generation pedigree and average relatedness coefficients. Our results highlighted that methods using marker-based relatedness coefficients performed as well as pedigree-based methods in presence of non-random mating (i.e. unequal male reproductive contributions, selfing), offering promising prospects to investigate in situ heritabilities in natural populations. In presence of maternal effects, only the use of pairwise relatednesses through pedigree information improved the accuracy of h2 estimates. In that case the amount of father-related offspring in the sibling design is the most critical. Overall, we showed that the method using both one-generation pedigree and average relatedness coefficients was the most robust to various ecological scenarios.
- Subjects :
- 0301 basic medicine
Genotyping Techniques
héritabilité
[SDV]Life Sciences [q-bio]
Population
Biology
heritability
unequal reproductive success
modelling
03 medical and health sciences
pédigrée
pedigree-free methods
marker-based relatednesses
maternal effects
breeding
Statistics
Genetics
Animals
Sibling
education
coefficient d'heritabilité
Ecology, Evolution, Behavior and Systematics
modélisation
education.field_of_study
Chimera
Reproduction
Siblings
Maternal effect
Selfing
Heritability
Mating system
030104 developmental biology
Genetics, Population
marqueur microsatellite
Inbreeding
microsatellite repeats
Biotechnology
Subjects
Details
- Language :
- English
- ISSN :
- 1755098X and 17550998
- Database :
- OpenAIRE
- Journal :
- Molecular Ecology Resources, Molecular Ecology Resources, Wiley/Blackwell, 2016, 16 (6), pp.1340-1352. ⟨10.1111/1755-0998.12536⟩, Molecular Ecology Resources 6 (16), 1340-1352. (2016)
- Accession number :
- edsair.doi.dedup.....ec85e3329ec269e0cd3598f1654309d4