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Regulation of senescence by eukaryotic translation initiation factor 5A: implications for plant growth and development
- Source :
- Trends in Plant Science. 9:174-179
- Publication Year :
- 2004
- Publisher :
- Elsevier BV, 2004.
-
Abstract
- Regulation of protein synthesis is increasingly being recognized as an important determinant of cell proliferation and senescence. In particular, recent evidence indicates that eukaryotic translation initiation factor 5A (eIF-A) plays a pivotal role in this determination. Separate isoforms of eIF-5A appear to facilitate the translation of mRNAs required for cell division and cell death. This raises the possibility that eIF-5A isoforms are elements of a biological switch that is in one position in dividing cells and in another position in dying cells. Changes in the position of this putative switch in response to physiological and environmental cues are likely to have a significant impact on plant growth and development.
- Subjects :
- Genetics
Regulation of gene expression
Senescence
Aging
Programmed cell death
Cell Death
Cell division
Cell Survival
Cell growth
Molecular Sequence Data
Arabidopsis
RNA-Binding Proteins
Translation (biology)
Plant Science
EIF4A1
Biology
Cell biology
Gene Expression Regulation, Plant
Peptide Initiation Factors
Protein biosynthesis
Protein Isoforms
Amino Acid Sequence
Protein Processing, Post-Translational
Cell Division
Conserved Sequence
Subjects
Details
- ISSN :
- 13601385
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Trends in Plant Science
- Accession number :
- edsair.doi.dedup.....ec71f57978d9a500d25899abd8884ce1