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Lymphoproliferative Disorders Presenting as Mediastinal Neoplasms
- Source :
- Seminars in Thoracic and Cardiovascular Surgery. 12:290-300
- Publication Year :
- 2000
- Publisher :
- Elsevier BV, 2000.
-
Abstract
- Lymphoproliferative disorders may present in any organ of the body. The mediastinum is an uncommon location for presentation of these heterogeneous disorders, but involvement of the mediastinum may be the sole site of disease for several aggressive lymphomas. Both Hodgkin's disease and non-Hodgkin's lymphoma may present in the mediastinum. The most common types of non-Hodgkin's lymphoma involving the mediastinum include lymphoblastic lymphoma and mediastinal large cell lymphoma. These lymphomas most commonly develop in the anterior mediastinum but may be seen in the middle and posterior mediastinum. Symptoms associated with a mediastinal presentation of a lymphoproliferative disorder are often attributable to compression of mediastinal structures (eg, superior vena cava syndrome) or invasion of thoracic structures such as the pericardium or pleura. Although staging can be performed with routine imaging studies, surgical intervention is often required to ensure accurate histologic diagnosis of these lymphomas. Once a diagnosis has been established, therapeutic modalities usually include chemotherapy and/or radiotherapy.
- Subjects :
- Pulmonary and Respiratory Medicine
medicine.medical_specialty
Pathology
Lymphoma
Lymphoproliferative disorders
Mediastinal Neoplasms
immune system diseases
hemic and lymphatic diseases
Humans
Medicine
Neoplasm Staging
Superior vena cava syndrome
business.industry
Lymphoblastic lymphoma
Large-cell lymphoma
Mediastinum
General Medicine
respiratory system
medicine.disease
Mediastinal Neoplasm
respiratory tract diseases
Non-Hodgkin's lymphoma
surgical procedures, operative
medicine.anatomical_structure
Surgery
Radiology
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 10430679
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Seminars in Thoracic and Cardiovascular Surgery
- Accession number :
- edsair.doi.dedup.....ec2b7682716c7ae8e799d5aed8f94477