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Role and analysis of monocyte subsets in cardiovascular disease

Authors :
Karlheinz Peter
Claudia Monaco
Christian Weber
Gunnar H. Heine
Michael Hristov
Johann Wojta
Eduard Shantsila
Imo E. Hoefer
Giuseppina Caligiuri
Agneta Siegbahn
Tomasz J. Guzik
Gregory Y.H. Lip
Ed Rainger
Sabine Steffens
Source :
Thrombosis and Haemostasis, 116(4), 626. Schattauer GmbH
Publication Year :
2016
Publisher :
Georg Thieme Verlag KG, 2016.

Abstract

SummaryMonocytes as cells of the innate immunity are prominently involved in the development of atherosclerotic lesions. The heterogeneity of blood monocytes has widely been acknowledged by accumulating experimental and clinical data suggesting a differential, subset-specific contribution of the corresponding subpopulations to the pathology of cardiovascular and other diseases. This document re-evaluates current nomenclature and summarises key findings on monocyte subset biology to propose a consensus statement about phenotype, separation and quantification of the individual subsets.Note: The review process for this paper was fully handled by Lina Badimon, Section Editor.

Details

ISSN :
2567689X and 03406245
Volume :
116
Database :
OpenAIRE
Journal :
Thrombosis and Haemostasis
Accession number :
edsair.doi.dedup.....ebf8447722147162393e37dd6502482b