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60PV Related Lesions in HIV Positive Subjects on HAART: Study of Viral Markers of Cervical Neoplasia Progression
- Source :
- Retrovirology, Vol 2, Iss Suppl 1, p P60 (2005)
- Publication Year :
- 2005
- Publisher :
- BMC, 2005.
-
Abstract
- Methods HIV pos women (N = 410) were followed since 1995 in a longitudinal study. Each one undergo periodic (6–12 months) colposcopy, PAP smear, biopsy if needed, and cervical sampling for HPV testing. HIV related parameters (CD4, HIV-RNA, ART) are recorded and related to cervical disease. HPV typing is performed by reverse hybridisation assays, viral load by in-house real time PCR and viral expression by E6/E7 mRNA detection. The Mann-Whitney rank sum test for non-parametric data and the association between discrete variables by Chi-square test of Fisher exact test were applied.
- Subjects :
- Colposcopy
Oncology
lcsh:Immunologic diseases. Allergy
medicine.medical_specialty
Longitudinal study
medicine.diagnostic_test
biology
business.industry
symbols.namesake
Infectious Diseases
Real-time polymerase chain reaction
Virology
Internal medicine
Biopsy
Immunology
medicine
symbols
biology.protein
Sampling (medicine)
Antibody
business
lcsh:RC581-607
Viral load
Fisher's exact test
Subjects
Details
- Language :
- English
- ISSN :
- 17424690
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Retrovirology
- Accession number :
- edsair.doi.dedup.....ebe75364e91d4459bda0de4bf4eefe8d