Safety assessment of fermented jackfruit ( Artocarpus heterophyllus ) pulp and leaves in Sprague‐Dawley rats

Fermented jackfruit (Artocarpus heterophyllus) extracts were produced using pure symbiotic culture of bacteria and yeast (SCOBY) under controlled fermentation process. Both female and male Sprague‐Dawley rats were orally administrated with 4,000 mg/kg of fermented jackfruit pulp and leaves extracts for 28 consecutive days. Body weight of rats was recorded at 1‐week interval until necropsy day. There was no mortality reported along the experiment with no significant differences (p > .05) record among organ histopathology and blood biochemical parameters in treated groups when compared to control group. Interestingly, there were significant differences (p
No toxicity symptoms were observed in Sprague‐Dawley rats for both sexes after 28 days oral administration with fermented jackfruit pulp and leaves. There were significant differences (p