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Insulin related lipodystrophic lesions and hypoglycemia: Double standards?
- Publication Year :
- 2018
-
Abstract
- Lipohypertophy (LH) is the most common skin complication of incorrect injection technique which does not only represent an aesthetic defect but also severely disrupts insulin pharmacokinetics/pharmacodynamics. As a consequence of that, hormone release is delayed and unexplained/unpredictable hypoglycemia occurs, both deteriorating metabolic control while negatively affecting adherence to treatment and quality of life. The economic burden due to unwanted intra-LH injections is accounted for by inappropriately high insulin requirements, increased emergency-related hospitalizations, and loss of work days. Greater attention has to be paid by diabetes care teams to education programs with periodic refreshers to achieve better metabolic control and reduce the economic burden of diabetes.
- Subjects :
- Pediatrics
medicine.medical_specialty
Lipodystrophy
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
030209 endocrinology & metabolism
030204 cardiovascular system & hematology
Hypoglycemia
Diabete
Injection technique
03 medical and health sciences
0302 clinical medicine
Diabetes mellitus
Internal Medicine
medicine
Humans
Hypoglycemic Agents
Insulin
Randomized Controlled Trials as Topic
Hypoglycemic Agent
business.industry
Lipohypertrophy
General Medicine
medicine.disease
Injection Site Reaction
Metabolic control analysis
Pharmacodynamics
business
Complication
Human
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....ebd2c618603718b3c4ce1810f025252c