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Human Papillomavirus E6 biosensing: Current progression on early detection strategies for cervical Cancer

Authors :
Sharipah Nadzirah
N. A. Parmin
Amilia Afzan
Zulida Rejali
M. N. A. Uda
Uda Hashim
Subash C. B. Gopinath
Source :
International Journal of Biological Macromolecules. 126:877-890
Publication Year :
2019
Publisher :
Elsevier BV, 2019.

Abstract

Prognosis of early cancer detection becomes one of the tremendous issues in the medical health system. Medical debates among specialist doctor and researcher in therapeutic approaches became a hot concern for cervix cancer deficiencies early screening, risk factors cross-reaction, portability device, rapid and free labeling system. The electrical biosensing based system showed credibility in higher specificity and selectivity due to hybridization of DNA duplex between analyte target and DNA probes. Electrical DNA sensor for cervix cancer has attracted too many attentions to researcher notification based on high performance, easy to handle, rapid system and possible to miniaturize. This review explores the current progression and future insignificant for HPV E6 genobiosensing for early Detection Strategies of Cervical Cancer.

Details

ISSN :
01418130
Volume :
126
Database :
OpenAIRE
Journal :
International Journal of Biological Macromolecules
Accession number :
edsair.doi.dedup.....ebb5e6c552126ba4a2cc2d2c196be212
Full Text :
https://doi.org/10.1016/j.ijbiomac.2018.12.235