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Novel interpenetrating polymer network provides significant and long‐lasting improvements in hydration to the skin from different body areas
- Source :
- Journal of Cosmetic Dermatology
- Publication Year :
- 2019
- Publisher :
- John Wiley and Sons Inc., 2019.
-
Abstract
- Background Hydration and moisturization both impact skin quality, directly reflecting its appearance. Signs and onset of dehydration-related skin aging are region-specific and require tailored treatment to be effective. Aims To test the hydrating effects of formulas containing a novel 3-dimensional 3-polymer interpenetrating network (3D3P-IPN) to deliver humectants and actives to specific body sites. Methods Two clinical studies were conducted focused on the skin under eyes and body (arms/legs). Healthy women ages 25-65 (eyes) or 35-65 (body) with mild to moderate dry and aged skin were enrolled. Study product containing the 3D3P-IPN and tailored actives was applied twice daily for 8 weeks on the periorbital area and for 4 weeks on the body. Changes in skin attributes were measured by biophysical instrumentation for hydration, dark circles, skin color, elasticity and transepidermal water loss, and by clinical grading and subject self-assessment. Results Significant improvements in hydration and skin smoothing were demonstrated in both studies. In the periorbital region, actives and humectants delivered by the 3D3P-IPN also led to significant improvements in dark circles, fine lines/crow's feet, puffiness, restoring radiance, and overall younger-looking appearance. On the arms and legs, there were significant reductions in crepiness and dullness. The arms and legs also had improvements in tactile and visual skin texture, radiance, and general healthy look. Improvements were immediate and persisted through the end of both studies. Conclusion The 3D3P-IPN provides immediate and long-lasting improvements in skin hydration and overall healthy appearance regardless of the targeted application site.
- Subjects :
- Periorbital region
Long lasting
Adult
Polymers
under‐eye circles
Dentistry
TIVI
Skin Pigmentation
Dermatology
Basic Science Cosmectic Dermatology Articles
Administration, Cutaneous
Skin Aging
030207 dermatology & venereal diseases
03 medical and health sciences
Skin hydration
0302 clinical medicine
Application site
Cosmeceuticals
Medicine
Humans
skin hydration
Aged
Skin
interpenetrating polymer network
Transepidermal water loss
Leg
business.industry
Original Contribution
Middle Aged
Tailored treatment
Skin Care
Water Loss, Insensible
Elasticity
Treatment Outcome
030220 oncology & carcinogenesis
Skin color
Face
Arm
Female
business
Subjects
Details
- Language :
- English
- ISSN :
- 14732165 and 14732130
- Volume :
- 19
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of Cosmetic Dermatology
- Accession number :
- edsair.doi.dedup.....eb639c2eb9352c77c12b5d95f4b53bfc